Fitz-Hugh Curtis Syndrome
Description of a clinical case and knowledge update
Keywords:
STAJANO SYNDROME, FITZ-HUGH-CURTIS SYNDROME
Abstract
The Fitz-Hugh-Curtis syndrome is a rare clinical presentation of upper genital infections, characterized by pain in the right hypochondrium, few pelvic symptoms, and „violin strings“ hepatophrenic adhesions. This unusual clinical presentation leads to frequent late or erroneous diagnoses, such as cholecystitis, appendicitis, urolithiasis or hepatophrenic abscesses.
Based on the clinical case presented, a historical and chronological review of knowledge and publications over time, on this particular clinical presentation was conduct
References
1) Blanco M, Larrañaga N, Jaramillo D, Roccatagliata N, de Vedia M, Vallejos J. Síndrome Fitz-Hugh-Curtis. Medicina (B. Aires) 2021; 81(5):873, 2021.
2) Pouey E, Stajano C. Las reacciones del peritoneo supracéliaco en ginecología, An Fac Med 1920; 5:202.
3) Stajano C. La reacción frénica en ginecología e interpretación fisio-lógica. An Fac Med 1920; 5:722.
4) Stajano C. La reacción frénica en ginecología. Semana Médica (B. Aires), 1920; 27:243-8.
5) Stajano C. Phrenic reaction in gynecology. JAMA 1921; 76(10):690.
6) Stajano C. Reaction phrénique et infection genitale. Gynecol Obstétr (París); 1922; 1:42-8.
7) Adair F. Diaphragmatic reaction in genital infection. Stajano C: Gy-necologie te Obstetrique, 1922, VI, 44. Am J Obstet Gynecol 1923; 6(4):508.
8) Curtis A. A cause of adhesions in the right upper quadrant. JAMA 1930; 94(16):1221-2.
9) Fitz-Hugh TJr. Acute gonococcic peritonitis of the right upper quad-rant in women. JAMA 1934; 102(25):2094-6.
10) Müller-Schoop J, Wang S, Munzinger J, Schläpfer H, Knoblauch M, Tammann R. Chlamydia trachomatis as possible cause of perito-nitis and perihepatitis in young women. Br Med J 1978; 1(6119):1022-4. doi: 10.1136/bmj.1.6119.1022.
11) Lopez-Zeno J, Keith L, Berger G. The Fitz-Hugh-Curtis syn-drome revisited. Changing perspectives after half a century. J Re-prod Med 1985; 30(8):567-82.
12) Kimball M, Knee S. Gonococcal perihepatitis in a male. The Fitz-Hugh--Curtis syndrome. N Engl J Med 1970; 282(19):1082-4. doi: 10.1056/NEJM197005072821908.
13) Sharma J, Malhotra M, Arora R. Fitz-Hugh-Curtis syndrome as a result of genital tuberculosis: a report of three cases. Acta Obstet Gynecol Scand 2003; 82(3):295-7. doi: 10.1034/j.1600-0412.2003.820302.x.
14) Coremans L, de Clerck F. Fitz-Hugh-Curtis syndrome associ-ated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. BMC Gastroenterol 2018; 18(1):42. doi: 10.1186/s12876-018-0768-0.
15) Flores Sánchez I, Gutiérrez Salinas J, Calderón Tapia J, Cer-vantes Chávez J. Síndrome de Fitz-Hugh-Curtis asociado con Myco-plasma Hominis: caso clínico. Ginecol Obstet Mex 2011; 79(10):637-41.
16) Demelo P, González Munera A, Tejerina F, Bernaldo J. Sín-drome de Fitz-Hugh-Curtisen fase subaguda/crónica. Rev Clin Esp. 2013; 213(5):e49. doi: 10.1016/j.rce.2013.01.004.
17) Hong D, Choi M, Chong G, Yi J, Seong W, Lee Y, et al. Fitz-Hugh-Curtis Syndrome: single centre experiences. J Obstet Gynaecol 2010; 30(3):277-80. doi: 10.3109/01443610903576282.
18) Litt I, Cohen M. Perihepatitis associated with salpingitis in ad-olescents. JAMA 1978; 240(12):1253-4.
19) Godinjak Z, Idrizbegović E. Should diagnostic hysteroscopy be a routine procedure during diagnostic laparoscopy in infertile wom-en? Bosn J Basic Med Sci 2008; 8(1):44-7. doi: 10.17305/bjbms.2008.2996.
20) Stajano C. Las leyes del dolor visceral. Soca 1930; 2(17).
21) Stajano C. Fisiopatología clínica del dolor en ginecología. Soca 1931; 2(18):11-4.
22) Hunter R, Cicinelli E, Einer-Jensen N. Peritoneal fluid as an unrecognised vector between female reproductive tissues. Acta Obstet Gynecol Scand 2007; 86(3):260-5. doi: 10.1080/00016340601155098.
23) Hamdan M, Johanet H, Benhamou G. The Fitz-Hugh-Curtis syndrome in a man revealed by ectopic appendicitis. Eur J Med 1992; 1(5):314-5.
24) Davidson A, Hawkins D. Pleuritic pain: Fitz Hugh Curtis syn-drome in a man. Br Med J (Clin Res Ed) 1982; 284(6318):808. doi: 10.1136/bmj.284.6318.808.
25) You J, Kim M, Chung H, Chung Y, Park I, et al. Clinical features of Fitz-Hugh-Curtis syndrome in the emergency department. Yonsei Med J 2012; 53(4):753-8. doi: 10.3349/ymj.2012.53.4.753.
26) Tulandi T, Falcone T. Incidental liver abnormalities at lapa-roscopy for benign gynecologic conditions. J Am Assoc Gynecol La-parosc 1998; 5(4):403-6. doi: 10.1016/s1074-3804(98)80055-8.
27) Ricci P, Lema R, Solá V, Fernández C, Fabres C, Fernández E, et al. Fitz-Hugh-Curtis syndrome: three cases of incidental diagnosis during laparoscopy. J Obstet Gynaecol 2008; 28(3):352-4. doi: 10.1080/01443610802058411.
28) Burton E, McKeating J, Stahlfeld K. Laparoscopic management of a small bowel obstruction of unknown cause. JSLS 2008; 12(3):299-302.
29) Abul-Khoudoud O, Khabbaz A, Butcher C, Farha M. Mechanical partial small bowel obstruction in a patient with Fitz-Hugh-Curtis syndrome. J Laparoendosc Adv Surg Tech A 2001; 11(2):111-4. doi: 10.1089/109264201750162437.
30) Choy J, Sethi V, Mosco-Guzman J, Hoffman T, Connelly W. A diagnosis not to miss: a case of Fitz-Hugh-Curtis syndrome. Case Rep Infect Dis 2022; 2022:1185314. doi: 10.1155/2022/1185314.
31) Uruguay. Ministerio de Salud Pública. Guía de diagnóstico, tratamiento, prevención y vigilancia de las infecciones de transmi-sión sexual. Montevideo: MSP, 2018.
2) Pouey E, Stajano C. Las reacciones del peritoneo supracéliaco en ginecología, An Fac Med 1920; 5:202.
3) Stajano C. La reacción frénica en ginecología e interpretación fisio-lógica. An Fac Med 1920; 5:722.
4) Stajano C. La reacción frénica en ginecología. Semana Médica (B. Aires), 1920; 27:243-8.
5) Stajano C. Phrenic reaction in gynecology. JAMA 1921; 76(10):690.
6) Stajano C. Reaction phrénique et infection genitale. Gynecol Obstétr (París); 1922; 1:42-8.
7) Adair F. Diaphragmatic reaction in genital infection. Stajano C: Gy-necologie te Obstetrique, 1922, VI, 44. Am J Obstet Gynecol 1923; 6(4):508.
8) Curtis A. A cause of adhesions in the right upper quadrant. JAMA 1930; 94(16):1221-2.
9) Fitz-Hugh TJr. Acute gonococcic peritonitis of the right upper quad-rant in women. JAMA 1934; 102(25):2094-6.
10) Müller-Schoop J, Wang S, Munzinger J, Schläpfer H, Knoblauch M, Tammann R. Chlamydia trachomatis as possible cause of perito-nitis and perihepatitis in young women. Br Med J 1978; 1(6119):1022-4. doi: 10.1136/bmj.1.6119.1022.
11) Lopez-Zeno J, Keith L, Berger G. The Fitz-Hugh-Curtis syn-drome revisited. Changing perspectives after half a century. J Re-prod Med 1985; 30(8):567-82.
12) Kimball M, Knee S. Gonococcal perihepatitis in a male. The Fitz-Hugh--Curtis syndrome. N Engl J Med 1970; 282(19):1082-4. doi: 10.1056/NEJM197005072821908.
13) Sharma J, Malhotra M, Arora R. Fitz-Hugh-Curtis syndrome as a result of genital tuberculosis: a report of three cases. Acta Obstet Gynecol Scand 2003; 82(3):295-7. doi: 10.1034/j.1600-0412.2003.820302.x.
14) Coremans L, de Clerck F. Fitz-Hugh-Curtis syndrome associ-ated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. BMC Gastroenterol 2018; 18(1):42. doi: 10.1186/s12876-018-0768-0.
15) Flores Sánchez I, Gutiérrez Salinas J, Calderón Tapia J, Cer-vantes Chávez J. Síndrome de Fitz-Hugh-Curtis asociado con Myco-plasma Hominis: caso clínico. Ginecol Obstet Mex 2011; 79(10):637-41.
16) Demelo P, González Munera A, Tejerina F, Bernaldo J. Sín-drome de Fitz-Hugh-Curtisen fase subaguda/crónica. Rev Clin Esp. 2013; 213(5):e49. doi: 10.1016/j.rce.2013.01.004.
17) Hong D, Choi M, Chong G, Yi J, Seong W, Lee Y, et al. Fitz-Hugh-Curtis Syndrome: single centre experiences. J Obstet Gynaecol 2010; 30(3):277-80. doi: 10.3109/01443610903576282.
18) Litt I, Cohen M. Perihepatitis associated with salpingitis in ad-olescents. JAMA 1978; 240(12):1253-4.
19) Godinjak Z, Idrizbegović E. Should diagnostic hysteroscopy be a routine procedure during diagnostic laparoscopy in infertile wom-en? Bosn J Basic Med Sci 2008; 8(1):44-7. doi: 10.17305/bjbms.2008.2996.
20) Stajano C. Las leyes del dolor visceral. Soca 1930; 2(17).
21) Stajano C. Fisiopatología clínica del dolor en ginecología. Soca 1931; 2(18):11-4.
22) Hunter R, Cicinelli E, Einer-Jensen N. Peritoneal fluid as an unrecognised vector between female reproductive tissues. Acta Obstet Gynecol Scand 2007; 86(3):260-5. doi: 10.1080/00016340601155098.
23) Hamdan M, Johanet H, Benhamou G. The Fitz-Hugh-Curtis syndrome in a man revealed by ectopic appendicitis. Eur J Med 1992; 1(5):314-5.
24) Davidson A, Hawkins D. Pleuritic pain: Fitz Hugh Curtis syn-drome in a man. Br Med J (Clin Res Ed) 1982; 284(6318):808. doi: 10.1136/bmj.284.6318.808.
25) You J, Kim M, Chung H, Chung Y, Park I, et al. Clinical features of Fitz-Hugh-Curtis syndrome in the emergency department. Yonsei Med J 2012; 53(4):753-8. doi: 10.3349/ymj.2012.53.4.753.
26) Tulandi T, Falcone T. Incidental liver abnormalities at lapa-roscopy for benign gynecologic conditions. J Am Assoc Gynecol La-parosc 1998; 5(4):403-6. doi: 10.1016/s1074-3804(98)80055-8.
27) Ricci P, Lema R, Solá V, Fernández C, Fabres C, Fernández E, et al. Fitz-Hugh-Curtis syndrome: three cases of incidental diagnosis during laparoscopy. J Obstet Gynaecol 2008; 28(3):352-4. doi: 10.1080/01443610802058411.
28) Burton E, McKeating J, Stahlfeld K. Laparoscopic management of a small bowel obstruction of unknown cause. JSLS 2008; 12(3):299-302.
29) Abul-Khoudoud O, Khabbaz A, Butcher C, Farha M. Mechanical partial small bowel obstruction in a patient with Fitz-Hugh-Curtis syndrome. J Laparoendosc Adv Surg Tech A 2001; 11(2):111-4. doi: 10.1089/109264201750162437.
30) Choy J, Sethi V, Mosco-Guzman J, Hoffman T, Connelly W. A diagnosis not to miss: a case of Fitz-Hugh-Curtis syndrome. Case Rep Infect Dis 2022; 2022:1185314. doi: 10.1155/2022/1185314.
31) Uruguay. Ministerio de Salud Pública. Guía de diagnóstico, tratamiento, prevención y vigilancia de las infecciones de transmi-sión sexual. Montevideo: MSP, 2018.
Published
2023-03-16
How to Cite
1.
Rodríguez Escudero F. Fitz-Hugh Curtis Syndrome. Rev. Méd. Urug. [Internet]. 2023Mar.16 [cited 2024Dec.18];39(1):e704. Available from: https://www2.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/1022
Section
Clinical Cases
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