Spontaneous pneumomediastinum as a complication of inhalant drug use

  • Patricia López Penza Universidad de la República, Facultad de Medicina, Hospital Maciel, Clínica Quirúrgica 3, Residente de Cirugía
  • Martín Odriozola Universidad de la República, Facultad de Medicina, Hospital Maciel, Clínica Quirúrgica 3, Prof. Adjunto
  • Luis Ruso Universidad de la República, Facultad de Medicina, Hospital Maciel, Clínica Quirúrgica 3, Profesor Director
Keywords: MEDIASTINAL EMPHYSEMA, COCAINE-RELATED DISORDERS

Abstract

Pneumomediastinum was described by Hamman in 1939, and it was Macklin who delineated the pathogenesis in 1944(1). It is a condition in which air is present in the mediastinum, and we say it is spontaneous when it is presented in the absence of other associated pathologies. It is a benign condition, infrequent, a self-limiting disease that may be associated with pneumothorax. In this study we present two cases of spontaneous pneumomediastinum, without pneumothorax, which highlight the concomitance of cocaine and cocaine base paste inhalation.

References

(1) Macklin KT, Macklin C. Malignant intertitial emphyma of lungs and mediastinum as an infant occult complications in many repiratory disease and other condictions. Medicina (Baltimore) 1944; 23: 281-358.
(2) Pilar B, Arce J. Neumomediastino espontáneo: enfisema retofaringeo forma de presentación no habitual. Rev Chil Radiol 2005; 3(11): 116-21.
(3) Park D, Pierson D. Pneumomediastinun and mediastinitis. In: Nadel JA, Mason RJ, Bradley VC, Murray JF, eds. Murray and Nadel´s textbook of respiratory medicine. Philadelphia: WB Saunders, 2000: 2095-214.
(4) De La Cruz Morón I, Reyes Nuñez N, Rojas Box JL. Neumomediastino espontáneo en un consumidor de cocaina. Arch Bronconeumol 2000; 36(4): 231.
(5) Rubio J, Bioque J, Feu N, Martínez Pacual, García F, Muñoz. Neumomediastino en un fumador libre de pasta de cocaina. Servicio de
Neumologia del Hospital Universiatrio Reina Sofía, Córdoba. España. Disponibe en:http://www.neumosur.net/files/NS2000.12.4.A06.pdf
(Consultado: 6/6/2007).
(6) Gerazounis M, Athanassiadi K, Kalantazi N, Moustordas M. Spontaneous pneumomediastinum: a rare benign entity. J Thorac Cardivasc Surg 2003; 126(3): 774-6.
(7) Panacek EA, Singer AJ, Sherman BW, Prescott A, Rutherford WF. Spontaneus pneumomediastinum: clinical and natural history. Ann Emerg Med 1992; 21(10): 1222-7.
(8) Khouzam N. The cocaine user who looked like a bullfrog. Hosp Pract (Off Ed) 1986; 21(9): 157-8.
(9) Androuny A, Magnusson P. Pneumopericardium from cocaine inhalation. N Engl J Med 1985; 313(1): 48-9.
(10) Terán Prieto A. Todo lo que usted debe saber sobre las drogas estimulantes cocaína y anfetaminas: 70 p. Disponibe en: www.cajaespana.es/Images/LIBRO%20DROGAS% 20WEB_tcm25-14623.pdf(Consultado: 6/6/2007).
(11) Pascual F, Torres M, Calafat A, eds. Monografía Cocaína. 2001: 250 p. Disponibe en: http://www.medicinainformacion.com/psq_adicciones_libros2. htm(Consultado: 6/6/2007).
(12) Cocaína. Disponibe en: http://www.tecnociencia.es/especiales/cocaina/introduccion.htm (Consultado: 6/6/2007).
(13) Koullias GJ, Korkolis DP, Wang XJ, Hammond GL. Current assessment and management of spontaneous pneumomediastinum in 24 adult patients. Eur J Cardiothorac Surg 2004; 25(5): 852-5.
(14) Rello J, Net A. Complicaciones asociadas al consumo de cocaina. Med Clin (Barc) 1988; 91(11): 435
(15) Santiago Aguinaga IJ, Martínez-Bayarri M. Neumomediastino espontáneo: análisis de 16 casos. Emergencias 2000; 12: 321-5.
(16) Aroesky DJ, Stanley RB, Crockett DM. Pneumomediastinum and cervical emphysema from inhalation of "free based" cocaine: report of three cases. Otolaryngol Head Neck Surg
(17) Shesser R, Davis C, Edelstein S. Pneumomediastinun and pneumothorax after inhaling alkaloidal cocaine. Ann Emerg Med 1981; 10(4): 213-5.
(18) Langwieler TE, Steffani KD, Bogoesvki DP, Mann O, Izbicki JR. Spontaneous pneumomediastinum. Ann Thorac Surg 2004; 78(2): 711-3.
(19) McMahon DJ. Spontaneus pneumomediastinum. Am J Surg 1976; 131(5): 550-1.
Published
2007-12-31
How to Cite
1.
López Penza P, Odriozola M, Ruso L. Spontaneous pneumomediastinum as a complication of inhalant drug use. Rev. Méd. Urug. [Internet]. 2007Dec.31 [cited 2024Dec.18];23(4):260-4. Available from: https://www2.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/602