Fibromatosis mesentérica solitaria
Reporte de caso y revisión de la literatura
Palabras clave:
TUMOR DESMOIDE, TUMOR PELVIANO, FIBROMATOSIS INTESTINAL, MASA PELVIANA, INTESTINO DELGADO
Resumen
La fibromatosis mesentérica es un subtipo profundo de tumor desmoide (TD), un tumor benigno de origen fibroblástico localmente agresivo por su tendencia a infiltrar los tejidos adyacentes. Son raros, esporádicos y pueden asociarse con el síndrome de Gardner.
El tratamiento de elección es la resección completa, evitando la recurrencia local.
Comunicamos el caso clínico de una paciente con fibromatosis intrabdominal mesentérica única, bien circunscripta, que simulaba por la imagenología una masa de origen pelviano.
Citas
1) Kasper B. Systemic treatment approaches for sporadic desmoid-type fibromatosis: scarce evidence and recommendations. Oncol Res Treat 2015; 38(5):244-8. doi: 10.1159/000381909.
2) Ravi V, Patel SR, Raut CP, DeLaney TF. Desmoid tumors: epidemiology, risk factors, molecular pathogenesis, clinical presentation, diagnosis, and local therapy. UpToDate 2016.
3) Mahajan A, Singh M, Varma A, Sandhu GS, Singh M, Nagori R. Mesenteric fibromatosis presenting as a diagnostic dilemma: a rare differential diagnosis of right iliac fossa mass in an eleven year old-a rare case report. Case Rep Surg 2013; 2013:569578. doi: 10.1155/2013/569578.
4) Alvarado D, Ferrera de Erazo C. Fibromatosis. Reporte de 28 casos y actualización del tema. Departamento de Patología Hospital Escuela 1979-1987. Rev Méd Hondur 1988; 56(2):158-66.
5) Stoidis CN, Spyropoulos BG, Misiakos EP, Fountzilas CK, Paraskeva PP, Fotiadis CI. Surgical treatment of giant mesenteric fibromatosis presenting as a gastrointestinal stromal tumor: a case report. J Med Case Rep 2010; 4:314.
6) Howard J, Pollock R. Intra-abdominal and abdominal wall desmoid fibromatosis. Oncol Ther 2016; 4(1):57-72.
7) Burke AP, Sobin LH, Shekitka KM, Federspiel BH, Helwig EB. Intra-abdominal fibromatosis. A pathologic analysis of 130 tumors with comparison of clinical subgroups. Am J Surg Pathol 1990; 14(4):335-41.
8) Dinauer PA, Brixey CJ, Moncur JT, Fanburg-Smith JC, Murphey MD. Pathologic and MR imaging features of benign fibrous soft-tissue tumors in adults. Radiographics 2007; 27(1):173-87. doi: 10.1148/rg.271065065.
9) Yantiss RK, Spiro IJ, Compton CC, Rosenberg AE. Gastrointestinal stromal tumor versus intra-abdominal fibromatosis of the bowel wall: a clinically important differential diagnosis. Am J Surg Pathol 2000; 24(7):947-57.
10) Faria SC, Iyer RB, Rashid A, Ellis L, Whitman GJ. Desmoid tumor of the small bowel and the mesentery. AJR Am J Roentgenol 2004; 183(1):118. doi: 10.2214/ajr.183.1.1830118.
11) Ortega Pérez N, Fernández San Millán D, Montesdeoca Cabrera D, Pérez Alonso E, Hernández Hernández JR. Abdomen agudo como presentación de fibromatosis mesentérica. Acta Gastroenterol Latinoam 2019; 49(3):250-3.
12) Levy AD, Rimola J, Mehrotra AK, Sobin LH. From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics 2006; 26(1):245-64.
13) Misiak P, Piskorz L, Wcislo S, Jabloński S, Brocki M. Giant mesentery fibromatosis presenting as acute abdomen-case report. Contemp Oncol (Pozn) 2013; 17(5):468-9. doi: 10.5114/wo.2013.37224.
14) Hereditary Colorectal Tumors Registry; Bertario L, Russo A, Sala P, Eboli M, Giarola M, D’amico F, et al. Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis. Int J Cancer 2001; 95(2):102-7. doi: org/ 0.1002/1097-0215(20010320)95:2<102::AID-IJC1018>3.0.CO;2-8.
15) Rampone B, Pedrazzani C, Marrelli D, Pinto E, Roviello F. Updates on abdominal desmoid tumors. World J Gastroenterol 2007; 13(45):5985-8.
16) Giarola M, Wells D, Mondini P, Pilotti S, Sala P, Azzarelli A, et al. Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours. Br J Cancer 1998; 78(5):582-7.
17) Azizi L, Balu M, Belkacem A, Lewin M, Tubiana JM, Arrivé L. MRI features of mesenteric desmoid tumors in familial adenomatous polyposis. Am J Roentgenol 2005; 184(4):1128-35. doi: 10.2214/AJR.184.4.01841128.
18) Janssen M, van Broekhoven D, Cates J, Bramer W, Nuyttens J, Gronchi A, et al. Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis. Br J Surg 2017; 104(4):347-57. doi: 10.1002/bjs.10477.
2) Ravi V, Patel SR, Raut CP, DeLaney TF. Desmoid tumors: epidemiology, risk factors, molecular pathogenesis, clinical presentation, diagnosis, and local therapy. UpToDate 2016.
3) Mahajan A, Singh M, Varma A, Sandhu GS, Singh M, Nagori R. Mesenteric fibromatosis presenting as a diagnostic dilemma: a rare differential diagnosis of right iliac fossa mass in an eleven year old-a rare case report. Case Rep Surg 2013; 2013:569578. doi: 10.1155/2013/569578.
4) Alvarado D, Ferrera de Erazo C. Fibromatosis. Reporte de 28 casos y actualización del tema. Departamento de Patología Hospital Escuela 1979-1987. Rev Méd Hondur 1988; 56(2):158-66.
5) Stoidis CN, Spyropoulos BG, Misiakos EP, Fountzilas CK, Paraskeva PP, Fotiadis CI. Surgical treatment of giant mesenteric fibromatosis presenting as a gastrointestinal stromal tumor: a case report. J Med Case Rep 2010; 4:314.
6) Howard J, Pollock R. Intra-abdominal and abdominal wall desmoid fibromatosis. Oncol Ther 2016; 4(1):57-72.
7) Burke AP, Sobin LH, Shekitka KM, Federspiel BH, Helwig EB. Intra-abdominal fibromatosis. A pathologic analysis of 130 tumors with comparison of clinical subgroups. Am J Surg Pathol 1990; 14(4):335-41.
8) Dinauer PA, Brixey CJ, Moncur JT, Fanburg-Smith JC, Murphey MD. Pathologic and MR imaging features of benign fibrous soft-tissue tumors in adults. Radiographics 2007; 27(1):173-87. doi: 10.1148/rg.271065065.
9) Yantiss RK, Spiro IJ, Compton CC, Rosenberg AE. Gastrointestinal stromal tumor versus intra-abdominal fibromatosis of the bowel wall: a clinically important differential diagnosis. Am J Surg Pathol 2000; 24(7):947-57.
10) Faria SC, Iyer RB, Rashid A, Ellis L, Whitman GJ. Desmoid tumor of the small bowel and the mesentery. AJR Am J Roentgenol 2004; 183(1):118. doi: 10.2214/ajr.183.1.1830118.
11) Ortega Pérez N, Fernández San Millán D, Montesdeoca Cabrera D, Pérez Alonso E, Hernández Hernández JR. Abdomen agudo como presentación de fibromatosis mesentérica. Acta Gastroenterol Latinoam 2019; 49(3):250-3.
12) Levy AD, Rimola J, Mehrotra AK, Sobin LH. From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics 2006; 26(1):245-64.
13) Misiak P, Piskorz L, Wcislo S, Jabloński S, Brocki M. Giant mesentery fibromatosis presenting as acute abdomen-case report. Contemp Oncol (Pozn) 2013; 17(5):468-9. doi: 10.5114/wo.2013.37224.
14) Hereditary Colorectal Tumors Registry; Bertario L, Russo A, Sala P, Eboli M, Giarola M, D’amico F, et al. Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis. Int J Cancer 2001; 95(2):102-7. doi: org/ 0.1002/1097-0215(20010320)95:2<102::AID-IJC1018>3.0.CO;2-8.
15) Rampone B, Pedrazzani C, Marrelli D, Pinto E, Roviello F. Updates on abdominal desmoid tumors. World J Gastroenterol 2007; 13(45):5985-8.
16) Giarola M, Wells D, Mondini P, Pilotti S, Sala P, Azzarelli A, et al. Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours. Br J Cancer 1998; 78(5):582-7.
17) Azizi L, Balu M, Belkacem A, Lewin M, Tubiana JM, Arrivé L. MRI features of mesenteric desmoid tumors in familial adenomatous polyposis. Am J Roentgenol 2005; 184(4):1128-35. doi: 10.2214/AJR.184.4.01841128.
18) Janssen M, van Broekhoven D, Cates J, Bramer W, Nuyttens J, Gronchi A, et al. Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis. Br J Surg 2017; 104(4):347-57. doi: 10.1002/bjs.10477.
Publicado
2022-08-08
Cómo citar
1.
López Penza P, Pereira MN, Costa Paz C, Oreggia Carrau M. Fibromatosis mesentérica solitaria. Rev. Méd. Urug. [Internet]. 8 de agosto de 2022 [citado 8 de mayo de 2024];38(2):e38211. Disponible en: http://www2.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/892
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Casos Clínicos
