Trends in cancer mortality in Uruguay 1953 to 1997
Keywords:
NEOPLASMS, MORTALITY, MORTALITY RATE, URUGUAY
Abstract
Trends in cancer mortality in Uruguay between 1953 and 1997 were evaluated using the data obtained by the Statistics Division of the Ministry of Public Health. The National Institute of Statistics determined risk population. Specific mortality rates and age-adjusted mortality rates were calculated using the world population standards for different anatomic sites or groups of anatomic sites. In order to determine relative risks (RR) of death for each period, data were adjusted by Poisson regressive models. The definitive model included age and period as explicative variables.
Lung cancer in men constantly increased until the period 1983-1987 (RR 1.78), followed by a significant decrease (RR for the last period was 1.69). Prostatic cancer increased during the whole period (RR 1.70). On the other hand, gastric and oesophageal cancers showed a remarkable decrease (RR 0.41 and 0.66 respectively). Colo-rectal cancer exhibited an increase until the early 80s becoming stable along the last three five years-periods.
For women, rates of mammal cancer significantly increased during the whole period (RR 1.32), broncho-pulmonary cancer showed a notable increase during the last decade (RR 1.58) and recently kidney and ovarian cancers also showed significant increases. Gastric and oesophageal cancers rates decreased along the whole period (RR 0.31 and 0.33). Colo-rectal cancer rate stabilized during the last two decades after an initial increase.
Life style changes would be the main causes of these observed trends.
References
1) Ministerio de Salud Pública (Uruguay). División Estadística. Mortalidad clasificada por causa, sexo y edad. Montevideo: MSP, 1998.
2) De Stéfani E, Fierro L, Barrios E, Ronco A. Cancer Mortality Trends in Uruguay, 1953-91. Int J Cancer 1994; 56 ( 5): 634-9.
3) Instituto Nacional de Estadística (Uruguay). Variables estadísticas relevantes durante el Siglo XX. Área Socio-demográfica. ( Biblioteca en línea] Fascículo 1.1: Población. Montevideo: INE, 2001: 1-14 http://www.ine.gub.uy/biblioteca/publicaciones.htm (consulta: mayo 2002).
4) Smith P. Comparison between registries age-standardized rates. En: Muir C, Waterhouse J, Mack t, powell j, whelan s, eds, Cancer Incidence in Five Continents. Lyon: International Agency for Research on Cancer, 1987: 790-9 (vol V). (IARC scientific publications Nº 88).
5) Baker Ja, Nelder Rj. The GLIM system. Release 3.77. Oxford: Numerical Algorithms Group, 1985: 1-121.
6) Abella de Mutarelli M. Calidad del certificado de defunción en Uruguay. Reporte Epidemiológico (Semanal). OMS, 1986: 364-6.
7) Percy C, Muir CS. The international comparability of cancer mortality data: results of an international death certificate study. Am J Epidemiol 1989; 129: 934-46.
8) Vassallo JA, Barrios E. II Atlas de mortalidad por cáncer en el Uruguay. Montevideo: Comisión Honoraria de Lucha Contra el Cáncer, 1999: 1-283.
9) Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999; 83: 18-29.
10) De Stéfani E, Correa P, Oreggia F, Deneo-Pellegrini H, Fernández G, Zavala D, et al. Black tobacco, wine and mate in oropharyngeal cancer. A case-control study from Uruguay. Rev Epidem Sante Publ 1988; 36: 389-94.
11) De Stéfani E, Deneo-Pellegrini H, Mendilaharsu M, Ronco AL. Diet and Risk of the Upper Aerodigestive Tract. I-Foods. Oral Oncology 1999; 35: 17-21.
12) De Stéfani E, Ronco Al, Mendilaharsu M, Deneo- Pellegrini H. Diet and Risk of the Upper Aerodigestive Tract. II-Nutrients. Oral Oncology 1999; 35: 22-6.
13) Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993; 54: 594-606.
14) Howson CP, Hiyama T, Wynder EL. The decline in gastric cancer: Epidemiology of an unplanned triumph. Epidemiol Rev 1986; 8: 1-27.
15) Correa P, Fontham E, Williams Pickle L, Chen V, Lin Y, Haenszel W. Dietary determinants of gastric cancer in South Louisiana inhabitants. J Natl Cancer Inst 1985; 75: 645-54.
16) Barrios E, Fierro L, Ronco A, De Stefani E. Geographical differences of gastric cancer trends in Uruguay (remitido al Int J Epidemiology).
17) Buiatti E, Sorso B. Distribution of risk factors in Italy and in the host countries. In: Geddes M, Parkin DM, Khlat M, Balzi D, Buiatti E, eds. Cancer in Italian migrant populations. Lyon: International Agency for Research on Cancer, 1993 (IARC scientific publications No 123).
18) International Agency for Research on Cancer. Infection with Helicobacter Pylori. In: Schistosomes, liver flukes and Helicobacter Pylori. Lyon: International Agency for Research on Cancer, 1994; (vol 61): 177-240. (IARC monographs on the evaluation of carcinogenic risks to humans).
19) De Stéfani E, Muñoz N, Esteve J, Vasallo A, Victora C, Teuchmann S. Mate drinking, alcohol, tobacco, diet and esophageal cancer in Uruguay: a case-control study. Cancer Res 1990; 50: 426-31.
20) Boyle P, Zaridze Dg, Smans M. Descriptive epidemiology of colorectal cancer. Int J Cancer 1985; 36: 9-18.
21) Smans M, Muir Cs, Boyle P. Atlas of cancer mortality in the European Economic Community. Lyon: International Agency for Research on Cancer, 1992: 68-9. (IARC scientific publication No 107).
22) Food and Agriculture Organisation of the United Nations. Food Balance Sheets, 1975-77 Average and Per Caput Food Supplies, 1961-65 Average. Rome: Food and Agriculture Organisation of the United Nations, 1980.
23) De Stéfani E, Carzoglio J, Deneo-Pellegrini H, Olivera L, Oreggia F. Laryngeal cancer in Uruguay (1958-1981): An epidemiologic study. Cancer 1985; 55: 214-6.
24) De Stéfani E, Correa P, Oreggia F, Leiva J, Rivero S, Fernandez G, et al. Risk factors for laryngeal cancer. Cancer 1987; 60: 3087-91.
25) Mc Kean-Cowdin R, Feigelson Hs, Ross Rk, Pike Mc, Henderson BE. Declining Cancer Rates in the 1990's. J Clin Oncol 2000; 18 ( 11): 2258-68.
26) International Agency for Research on Cancer. Tobacco smoking. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Lyon: International Agency for Research on Cancer, 1986: 1-421 (vol 38).
27) Blot WJ, Fraumeni JF. Cancer of the Lung and Pleura. In: Schottenfeld D, Fraumeni JF. Oxford: Cancer Epidemiology and Prevention, Oxford; Oxford University Press, 1996: 641.
28) De Stéfani E, Fierro L, Correa P, Carzoglio J, Deneo- Pellegrini H, Zavala D, et al. Type of tobacco and risk of lung cancer: a case-control study from Uruguay. Lung Cancer 1992; 8: 21-8.
29) World Cancer Research Fund. Food, Nutrition and the Prevention of Cancer: a global perspective. Washington: American Institute for Cancer Research, 1997: 310-23.
30) De Stéfani E, Fierro L, Barrios E, Ronco A. Tobacco, Alcohol, Diet and Risk of Prostatic Cancer. Tumori 1995; 81: 315- 20.
31) Parkin DM, Ferlay J, Pisani P. Cancer Incidence in Five Continents. Lyon: International Agency for Research on Cancer, 1997: 956-7 (vol VII).
32) Cuzick J, Boyle P. Trends in cervix cancer mortality. Cancer Surv 1988; 7: 417-39.
33) Miller AB. The Canadian experience of cervical cancer: incidence trends and a planned natural history investigation. In: Magnus K, ed. Trends in cancer incidence causes and practical implications. New York: Hemisphere Publishing: 1982.
34) Larrinaga M, Lateulade S, Balbi Jc, Mendilaharsu M, Fierro L, De Stefani E. Paridad, factores sexuales y riesgo de cáncer de cérvix uterino. Arch Med Int 1990; 12(4): 139-45.
35) Brinton La, Reeves Wc, Brenes MM, Herrero R, Britton Rc, Gaitan E, et al. Parity as a risk factor for cervical cancer. Am J Epidemiol 1989; 130: 486-96.
36) La Vecchia C, Negri E, Franceschi S, Parazzini F. Long-term impact of reproductive factors on cancer risk. Int J Cancer 1993; 53: 215-9.
2) De Stéfani E, Fierro L, Barrios E, Ronco A. Cancer Mortality Trends in Uruguay, 1953-91. Int J Cancer 1994; 56 ( 5): 634-9.
3) Instituto Nacional de Estadística (Uruguay). Variables estadísticas relevantes durante el Siglo XX. Área Socio-demográfica. ( Biblioteca en línea] Fascículo 1.1: Población. Montevideo: INE, 2001: 1-14 http://www.ine.gub.uy/biblioteca/publicaciones.htm (consulta: mayo 2002).
4) Smith P. Comparison between registries age-standardized rates. En: Muir C, Waterhouse J, Mack t, powell j, whelan s, eds, Cancer Incidence in Five Continents. Lyon: International Agency for Research on Cancer, 1987: 790-9 (vol V). (IARC scientific publications Nº 88).
5) Baker Ja, Nelder Rj. The GLIM system. Release 3.77. Oxford: Numerical Algorithms Group, 1985: 1-121.
6) Abella de Mutarelli M. Calidad del certificado de defunción en Uruguay. Reporte Epidemiológico (Semanal). OMS, 1986: 364-6.
7) Percy C, Muir CS. The international comparability of cancer mortality data: results of an international death certificate study. Am J Epidemiol 1989; 129: 934-46.
8) Vassallo JA, Barrios E. II Atlas de mortalidad por cáncer en el Uruguay. Montevideo: Comisión Honoraria de Lucha Contra el Cáncer, 1999: 1-283.
9) Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999; 83: 18-29.
10) De Stéfani E, Correa P, Oreggia F, Deneo-Pellegrini H, Fernández G, Zavala D, et al. Black tobacco, wine and mate in oropharyngeal cancer. A case-control study from Uruguay. Rev Epidem Sante Publ 1988; 36: 389-94.
11) De Stéfani E, Deneo-Pellegrini H, Mendilaharsu M, Ronco AL. Diet and Risk of the Upper Aerodigestive Tract. I-Foods. Oral Oncology 1999; 35: 17-21.
12) De Stéfani E, Ronco Al, Mendilaharsu M, Deneo- Pellegrini H. Diet and Risk of the Upper Aerodigestive Tract. II-Nutrients. Oral Oncology 1999; 35: 22-6.
13) Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993; 54: 594-606.
14) Howson CP, Hiyama T, Wynder EL. The decline in gastric cancer: Epidemiology of an unplanned triumph. Epidemiol Rev 1986; 8: 1-27.
15) Correa P, Fontham E, Williams Pickle L, Chen V, Lin Y, Haenszel W. Dietary determinants of gastric cancer in South Louisiana inhabitants. J Natl Cancer Inst 1985; 75: 645-54.
16) Barrios E, Fierro L, Ronco A, De Stefani E. Geographical differences of gastric cancer trends in Uruguay (remitido al Int J Epidemiology).
17) Buiatti E, Sorso B. Distribution of risk factors in Italy and in the host countries. In: Geddes M, Parkin DM, Khlat M, Balzi D, Buiatti E, eds. Cancer in Italian migrant populations. Lyon: International Agency for Research on Cancer, 1993 (IARC scientific publications No 123).
18) International Agency for Research on Cancer. Infection with Helicobacter Pylori. In: Schistosomes, liver flukes and Helicobacter Pylori. Lyon: International Agency for Research on Cancer, 1994; (vol 61): 177-240. (IARC monographs on the evaluation of carcinogenic risks to humans).
19) De Stéfani E, Muñoz N, Esteve J, Vasallo A, Victora C, Teuchmann S. Mate drinking, alcohol, tobacco, diet and esophageal cancer in Uruguay: a case-control study. Cancer Res 1990; 50: 426-31.
20) Boyle P, Zaridze Dg, Smans M. Descriptive epidemiology of colorectal cancer. Int J Cancer 1985; 36: 9-18.
21) Smans M, Muir Cs, Boyle P. Atlas of cancer mortality in the European Economic Community. Lyon: International Agency for Research on Cancer, 1992: 68-9. (IARC scientific publication No 107).
22) Food and Agriculture Organisation of the United Nations. Food Balance Sheets, 1975-77 Average and Per Caput Food Supplies, 1961-65 Average. Rome: Food and Agriculture Organisation of the United Nations, 1980.
23) De Stéfani E, Carzoglio J, Deneo-Pellegrini H, Olivera L, Oreggia F. Laryngeal cancer in Uruguay (1958-1981): An epidemiologic study. Cancer 1985; 55: 214-6.
24) De Stéfani E, Correa P, Oreggia F, Leiva J, Rivero S, Fernandez G, et al. Risk factors for laryngeal cancer. Cancer 1987; 60: 3087-91.
25) Mc Kean-Cowdin R, Feigelson Hs, Ross Rk, Pike Mc, Henderson BE. Declining Cancer Rates in the 1990's. J Clin Oncol 2000; 18 ( 11): 2258-68.
26) International Agency for Research on Cancer. Tobacco smoking. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Lyon: International Agency for Research on Cancer, 1986: 1-421 (vol 38).
27) Blot WJ, Fraumeni JF. Cancer of the Lung and Pleura. In: Schottenfeld D, Fraumeni JF. Oxford: Cancer Epidemiology and Prevention, Oxford; Oxford University Press, 1996: 641.
28) De Stéfani E, Fierro L, Correa P, Carzoglio J, Deneo- Pellegrini H, Zavala D, et al. Type of tobacco and risk of lung cancer: a case-control study from Uruguay. Lung Cancer 1992; 8: 21-8.
29) World Cancer Research Fund. Food, Nutrition and the Prevention of Cancer: a global perspective. Washington: American Institute for Cancer Research, 1997: 310-23.
30) De Stéfani E, Fierro L, Barrios E, Ronco A. Tobacco, Alcohol, Diet and Risk of Prostatic Cancer. Tumori 1995; 81: 315- 20.
31) Parkin DM, Ferlay J, Pisani P. Cancer Incidence in Five Continents. Lyon: International Agency for Research on Cancer, 1997: 956-7 (vol VII).
32) Cuzick J, Boyle P. Trends in cervix cancer mortality. Cancer Surv 1988; 7: 417-39.
33) Miller AB. The Canadian experience of cervical cancer: incidence trends and a planned natural history investigation. In: Magnus K, ed. Trends in cancer incidence causes and practical implications. New York: Hemisphere Publishing: 1982.
34) Larrinaga M, Lateulade S, Balbi Jc, Mendilaharsu M, Fierro L, De Stefani E. Paridad, factores sexuales y riesgo de cáncer de cérvix uterino. Arch Med Int 1990; 12(4): 139-45.
35) Brinton La, Reeves Wc, Brenes MM, Herrero R, Britton Rc, Gaitan E, et al. Parity as a risk factor for cervical cancer. Am J Epidemiol 1989; 130: 486-96.
36) La Vecchia C, Negri E, Franceschi S, Parazzini F. Long-term impact of reproductive factors on cancer risk. Int J Cancer 1993; 53: 215-9.
Published
2002-09-30
How to Cite
1.
Barrios E, Ronco Álvaro L, Fierro L, De Stéfani E, Vassallo JA. Trends in cancer mortality in Uruguay 1953 to 1997. Rev. Méd. Urug. [Internet]. 2002Sep.30 [cited 2024Nov.17];18(2):167-74. Available from: http://www2.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/992
Section
Original Articles
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
